Publications 2020


Latosinska A, Davalieva K, Makridakis M, Mullen W, Schanstra JP, Vlahou A, Mischak H, Frantzi M.

Molecular Changes in Tissue Proteome during Prostate Cancer Development: Proof-of-Principle Investigation.

Diagnostics (Basel). 2020 Aug 31;10(9):E655. doi: 10.3390/diagnostics10090655.

PMID: 32878211

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Frantzi M, Hupe MC, Merseburger AS, Schanstra JP, Mischak H, Latosinska A.

Omics Derived Biomarkers and Novel Drug Targets for Improved Intervention in Advanced Prostate Cancer.

Diagnostics (Basel). 2020 Aug 31;10(9):E658. doi: 10.3390/diagnostics10090658.

PMID: 32878288

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Maria Frantzi , Enrique Gomez-Gomez & Harald Mischak

Non-invasive biomarkers to guide intervention: towards personalized patient management in prostate cancer

Received 08 May 2020, Accepted 13 Jul 2020, Accepted author version posted online: 03 Aug 2020

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G. N. Baltas , F. A. Prieto, M. Frantzi, C. R. Garcia-Alonso, P. Rodriguez

Data Driven Modelling of Coronavirus Spread in Spain

CMC-Computers, Materials & Continua, Vol.64, No.3, pp. 1343-1357, 2020,


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Wendt R, He T, Latosinska A, Siwy J, Mischak H, Beige J.

Proteomic characterization of obesity-related nephropathy.

Clin Kidney J. 2020 Apr 15;13(4):684-692. doi: 10.1093/ckj/sfaa016. eCollection 2020 Aug.

PMID: 32905225

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Klein J, Buffin-Meyer B, Boizard F, Moussaoui N, Lescat O, Breuil B, Fedou C, Feuillet G, Casemayou A, Neau E, Hindryckx A, Decatte L, Levtchenko E, Raaijmakers A, Vayssière C, Goua V, Lucas C, Perrotin F, Cloarec S, Benachi A, Manca-Pellissier MC, Delmas HL, Bessenay L, Le Vaillant C, Allain-Launay E, Gondry J, Boudailliez B, Simon E, Prieur F, Lavocat MP, Saliou AH, De Parscau L, Bidat L, Noel C, Floch C, Bourdat-Michel G, Favre R, Weingertner AS, Oury JF, Baudouin V, Bory JP, Pietrement C, Fiorenza M, Massardier J, Kessler S, Lounis N, Auriol FC, Marcorelles P, Collardeau-Frachon S, Zürbig P, Mischak H, Magalhães P, Batut J, Blader P, Saulnier Blache JS, Bascands JL, Schaefer F, Decramer S, Schanstra JP; BIOMAN consortium.

Amniotic fluid peptides predict postnatal kidney survival in developmental kidney disease.

Kidney Int. 2020 Aug 1:S0085-2538(20)30894-2. doi: 10.1016/j.kint.2020.06.043. Online ahead of print.

PMID: 32750455

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Campbell RT, Jasilek A, Mischak H, Nkuipou-Kenfack E, Latosinska A, Welsh PI, Jackson CE, Cannon J, McConnachie A, Delles C, McMurray JJV.

The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure.

ESC Heart Fail. 2020 Aug;7(4):1595-1604. doi: 10.1002/ehf2.12708. Epub 2020 May 8.

PMID: 32383555

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Latosinska A, Siwy J, Faguer S, Beige J, Mischak H, Schanstra JP.

Value of Urine Peptides in Assessing Kidney and Cardiovascular Disease.

Proteomics Clin Appl. 2020 Jul 25:e2000027. doi: 10.1002/prca.202000027. Online ahead of print.

PMID: 32710812

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He T, Pejchinovski M, Mullen W, Beige J, Mischak H, Jankowski V.

Peptides in Blood, Urine and Dialysate: Towards Unravelling Renal Peptide Handling.

Proteomics Clin Appl. 2020 Jul 3:e2000029. doi: 10.1002/prca.202000029. Online ahead of print.

PMID: 32618437

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He T, Siwy J, Metzger J, Mullen W, Mischak H, Schanstra JP, Zürbig P, Jankowski V.

Associations of urinary polymeric immunoglobulin receptor peptides in the context of cardio-renal syndrome.

Sci Rep. 2020 May 19;10(1):8291. doi: 10.1038/s41598-020-65154-2.

PMID: 32427855

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Mischak H.

Datasharing: Obsolete? Impossible in times of GDPR ? Or mandatory in science?!

Eur J Clin Invest. 2020 Apr 19:e13244. doi: 10.1111/eci.13244. Online ahead of print.

PMID: 32306378

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Pejchinovski M, Mischak H.

Re-analysis of "Peptidomic analysis of cartilage and subchondral bone in OA patients".

Eur J Clin Invest. 2020 Apr 18:e13240. doi: 10.1111/eci.13240. Online ahead of print.

PMID: 32306374

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Weissinger EM, Basílio-Queirós D, Metzger J, Bieling LM, Ganser A.

Proteomics for hematopoietic stem cell transplantation.

Expert Rev Proteomics. 2020 Mar;17(3):201-206. doi: 10.1080/14789450.2020.1748501. Epub 2020 Apr 4.

PMID: 32228239

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Makridakis M, Kontostathi G, Petra E, Stroggilos R, Lygirou V, Filip S, Duranton F, Mischak H, Argiles A, Zoidakis J, Vlahou A.

Multiplexed MRM-based protein quantification of putative prognostic biomarkers for chronic kidney disease progression in plasma.

Sci Rep. 2020 Mar 16;10(1):4815. doi: 10.1038/s41598-020-61496-z.

PMID: 32179759

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Buffin-Meyer B, Tkaczyk M, Stańczyk M, Breuil B, Siwy J, Szaflik K, Talar T, Wojtera J, Krzeszowski W, Decramer S, Klein J, Schanstra JP.

A single-center study to evaluate the efficacy of a fetal urine peptide signature predicting postnatal renal outcome in fetuses with posterior urethral valves.

Pediatr Nephrol. 2020 Mar;35(3):469-475. doi: 10.1007/s00467-019-04390-9. Epub 2019 Nov 7.

PMID: 31701236

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Tofte N, Lindhardt M, Adamova K, Bakker SJL, Beige J, Beulens JWJ, Birkenfeld AL, Currie G, Delles C, Dimos I, Francová L, Frimodt-Møller M, Girman P, Göke R, Havrdova T, Heerspink HJL, Kooy A, Laverman GD, Mischak H, Navis G, Nijpels G, Noutsou M, Ortiz A, Parvanova A, Persson F, Petrie JR, Ruggenenti PL, Rutters F, Rychlík I, Siwy J, Spasovski G, Speeckaert M, Trillini M, Zürbig P, von der Leyen H, Rossing P;

Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial.

PRIORITY investigators. Lancet Diabetes Endocrinol. 2020 Apr;8(4):301-312. doi: 10.1016/S2213-8587(20)30026-7. Epub 2020 Mar 2.

PMID: 32135136

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Nkuipou-Kenfack E, Latosinska A, Yang WY, Fournier MC, Blet A, Mujaj B, Thijs L, Feliot E, Gayat E, Mischak H, Staessen JA, Mebazaa A, Zhang ZY

A novel urinary biomarker predicts 1-year mortality after discharge from intensive care.

French and European Outcome Registry in Intensive Care Unit Investigators. Crit Care. 2020 Jan 9;24(1):10. doi: 10.1186/s13054-019-2686-0.

PMID: 31918764

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Voigtländer T, Metzger J, Husi H, Kirstein MM, Pejchinovski M, Latosinska A, Frantzi M, Mullen W, Book T, Mischak H, Manns MP.



Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma.

J Biomed Sci. 2020 Jan 3;27(1):13. doi: 10.1186/s12929-019-0599-5.

PMID: 31900160

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Rosa Maria Bruno, Harald Mischak, Alexandre Persu

Multi-omics applied to fibromuscular dysplasia: first steps on a new research avenue

Cardiovasc Res . 2020 Jan 1;116(1):4-5. doi: 10.1093/cvr/cvz307.

PMID:: 31711122

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Siwy J, Ahonen L, Magalhães P, Frantzi M, Rossing P.

Metabolomic and Proteomic Techniques for Establishing Biomarkers and Improving Our Understanding of Pathophysiology in Diabetic Nephropathy.

Methods Mol Biol. 2020;2067:287-306. doi: 10.1007/978-1-4939-9841-8_18.

PMID: 31701458

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